Phenotypes and Genotypes: The Search for Influential Genes Van Florian Frommlet, Malgorzata Bogdan and David Ramsey is an English-language textbook focused on genetic association. This reference work provides a thorough overview of theory and methods for identifying genes that influence traits (phenotypes and genotypes).
The book covers techniques such as gene mapping through experimental crosses and genome-wide association studies. At its core is the application of model selection based on modified Bayesian information criteria for analyzing large-scale genomic data.
Key features:
- Comprehensive theoretical introduction to genetic association
- Explanation of statistical methods for locally tracking genes
- Use of simulations and practical examples
- Discussion of current challenges and a statistical appendix for background information
This work connects with disciplines such as computational biology, bioinformatics, and statistics, and is a valuable resource for professionals in the life sciences.