Phenotypes and Genotypes: The Search for Influential Genes by Florian Frommlet, Malgorzata Bogdan and David Ramsey is an English-language textbook about genetic association. This work is intended for students in higher education who are looking for deeper insight into genetics and statistics.
The book provides an extensive introduction to the role of genes in determining phenotypes and covers method developments for gene mapping and genome-wide association studies. Particular attention is given to model selection using customized Bayesian information criteria in large genotype datasets.
The authors present theoretical background and illustrate methods with simulations and real-world examples. In addition, current developments and open questions in genetic association are addressed. A comprehensive statistical reference section makes it suitable for readers with varying levels of prior knowledge.
In terms of content, this work aligns with topics such as taxonomy, systematics, and life sciences, and has been published in the Computational Biology series.