Phenotypes and Genotypes: The Search for Influential Genes van Florian Frommlet, Malgorzata Bogdan, David Ramsey is een Engelstalig gedrukt boek. Deze titel is geschikt voor studenten in het hoger onderwijs.
This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes).
Inhoudelijk sluit dit boek aan bij onderwerpen als Taxonomy and systematics, Probability and statistics, SCIENCE / Life Sciences / Taxonomy.
Serie: Computational Biology