This study book, written by Xianhai Huang and Robert G. Aslanian, addresses the process of drug discovery and development through in-depth case studies. It is intended for medicinal chemists and pharmaceutical scientists who are seeking practical knowledge about the successful and unsuccessful stages of drug development.
Contents
The book provides in-depth analyses of fourteen drugs and their therapeutic applications. The case studies highlight the full trajectory from discovery to market launch, with attention to pharmacology, drug design, metabolism, biology, and clinical trials.
- Stages of drug discovery and development, from idea to commercialization
- Important, life-saving medicines and therapeutic areas such as cardiovascular diseases, infections, cancer, and allergies
- Examples of prodrugs and inhalation medicines
- Investments and reasons why some drugs did not make it to the market
Each chapter ends with references to primary literature and is richly illustrated with tables and figures to make complex processes understandable. The introduction discusses current challenges within the pharmaceutical industry and future research directions.
Product specifications
- Author: Xianhai Huang, Robert G. Aslanian
- Publisher: John Wiley & Sons Inc
- Publication date: 2012-06-15
- Number of pages: 488
- ISBN: 9780470601815
- Theme: Pharmaceutical chemistry and technology
- BISAC: TECHNOLOGY & ENGINEERING / Pharmaceutical
About the authors
Xianhai Huang, PhD, is Principal Scientist at Merck Research Laboratories and co-inventor of more than forty patents. He has made important contributions to the synthesis of antitumor agents.
Robert G. Aslanian, PhD, is an adjunct professor and former Senior Director of Medicinal Chemistry at Schering-Plough and Merck. He has more than twenty-five years of experience in the pharmaceutical industry and is a co-author of various patents and scientific publications.